Alberta BLOOM Clinical Research Study
Alberta BLOOM is a major research initiative at the University of Calgary aiming to discover how the maternal and infant microbiotas – all of the microbes living in and on the human body – impact infant and child health. By engaging mothers in biomedical research, Alberta BLOOM makes them active partners in the development of evidence-based policies and interventions that empower women to make healthy choices for their bodies and their babies.
Please check back soon for an updated list of current projects!
The Ecology of the Early Life Microbiome
We know we get colonized with trillions of microbes as soon as we are born, but how does this happen? Is there an evolutionarily conserved sequence of events, and if so, which ecological process(es) drive this? Given that modern humans live very different now than only 100 years ago, how does modern lifestyle influence this pattern of colonization during early life? We are trying to answer these questions using birth cohort studies in industrialized and non-industrialized countries.
The Early Life Microbiome in Asthma Development
Asthma is the chronic disease that affects most children around the world. What's even more worrisome is that its incidence continues to increase rapidly, and cases are becoming more severe. Research from Drs. Arrieta, Finlay and collaborators has shown that changes in the gut microbiome very in early in life can increase a baby's risk to develop asthma. Our lab is currently interested in finding more bacteria and fungi involved in this interesting association, exploring the immune mechanisms behind it, and finding ways to correct it. We are answering these questions using data from our human studies and modeling it in mouse models of airway inflammation.